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325 results found


Breast

Elacestrant in Various Combinations in Metastatic Breast Cancer

The purpose of this study is to determine whether an endocrine therapy drug approved by the U.S. Food and Drug Administration (FDA) called elacestrant is safe and effective when given in combination with one of ...


Other

BIVV020 for Prevention and Treatment of Antibody-Mediated Rejection in Adult Kidney Transplant Recipients

The purpose of the study is to evaluate whether an experimental medicine called BIVV020 can prevent antibody-mediated rejection (AMR) in patients with kidney transplants. BIVV020 is a type of antibody that binds to complement proteins. ...


Other

Strategies and Treatments for Hospitalized Patients With Respiratory Infections

The purpose of this study is to evaluate an investigational drug called ensitrelvir (S-217622) for treating people who are in the hospital with COVID-19. Researchers aim to determine whether ensitrelvir is safe and effective when ...


Other

SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...