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K-808 (Pemafibrate) in Primary Biliary Cholangitis

The purpose of this study is to determine the safety and effectiveness of an experimental drug called K-808 in participants with primary biliary cholangitis (PBC). K-808 (also called K-877-ER or pemafibrate) is designed to slow ...


Other

Prospective Registry to Investigate Treatment Options and Their Outcomes on Post-Traumatic Long Bones Defects

This study focuses on people who have a long bone defect (LBD), which is defined as a loss of bone tissue in any long bone of the arm or leg. Reconstructive surgery is often required. ...


Other

Lorundrostat in Uncontrolled Hypertension

This study focuses on individuals who have high blood pressure that is not well-controlled with their current medications (also known as uncontrolled hypertension) and who have received an experimental drug called MLS-101 or lorundrostat in ...


Prostate

High Five Trial: High-Risk Prostate Cancer

The purpose of this study is to compare 2 radiation schedules that can be used to treat patients with high-risk prostate cancer. One approach delivers a higher dose of radiation per treatment and uses fewer ...


Other

Cardiac Radioablation Versus Repeat Catheter Ablation in Ventricular Tachycardia

The purpose of this study is to evaluate whether an experimental medical device is safe and effective in performing a treatment called cardiac radioablation in patients who have had a previous catheter ablation procedure for ...