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HIS-Bundle Corrective Pacing in Heart Failure

The purpose of this study is to assess the effects of pacing-cardiac resynchronization therapy to a specific area of the heart called the His bundle (HIS-CRT), compared to biventricular pacemaker cardiac resynchronization therapy (BIV-CRT) on ...


Other

Symphony Thrombectomy System in the Treatment of Pulmonary Embolism

This study focuses on individuals who are scheduled to undergo a thrombectomy (procedure to remove a blood clot using a tube) to treat their pulmonary embolism (blood clot in the lung). The purpose of the ...


Melanoma

IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in Advanced Melanoma

This study focuses on adults with advanced melanoma (a type of skin cancer) that has spread or cannot be surgically removed. The purpose of the study is to determine whether an experimental drug called IMC-F106C, ...


Other

Cerebral Protection in Transcatheter Aortic Valve Replacement

The purpose of this study is to evaluate the safety and feasibility of an experimental filter system called the ProtEmbo Cerebral Protection System (ProtEmbo Device) in patients who are undergoing TAVR and have a risk ...


Hodgkin's Lymphoma

Comparing Standard Therapy With Immuno-Oncology Therapy for Children and Adults With Classic Hodgkin Lymphoma

The goal of this study is to compare the effects of brentuximab vedotin (BV) and nivolumab (NIVO) with standard therapy for people with early-stage Hodgkin lymphoma (HL) to determine which is more effective. HL is ...