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OHB-607 Compared to Standard Neonatal Care for the Prevention of Bronchopulmonary Dysplasia

Babies born prematurely often have problems with their lungs and breathing. The purpose of this study is to determine whether an experimental drug called mecasermin rinfabate (OHB-607) can decrease the risk of breathing problems and ...


Other

Belatacept With Delayed Tacrolimus Withdrawal Versus Standard-of-Care Tacrolimus in Heart Transplant Recipients

This study focuses on people who are on the waitlist to receive a heart transplant. Organ transplant recipients must take medications to suppress their immune system to prevent rejection of the transplanted organ (known as ...


Kidney

Risk-Adapted Treatment of Unilateral Favorable Histology Wilms Tumors

The purpose of this study is to improve outcomes for children with a diagnosis of favorable histology Wilms tumor (FHWT), a cancer type in which certain microscopic characteristics of tumor cells are associated with a ...


Breast

Belzutifan Plus Fulvestrant in ER-Positive, HER2-Negative Unresectable Locally Advanced or Metastatic Breast Cancer

This study focuses on people who have been diagnosed with estrogen receptor-positive (ER+)/HER2-negative breast cancer that cannot be removed surgically, has come back, or has spread to other areas of the body, and/or has grown ...


Other

DNTH103 in Adults with Multifocal Motor Neuropathy (MOMENTUM)

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an experimental medication called DNTH103 in people with multifocal motor neuropathy (MMN), a condition that causes progressive muscle weakness. The study ...