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ARGENX

Primary objective is to evaluate the safety and tolerability of efgartigimod PH20 SC in kidney transplant recipients diagnosed with AMR.


Other

Long-term Safety and Efficacy of Tulisokibart in Crohn’s Disease or Ulcerative Colitis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) compared with placebo (inactive substance) in people with Crohn’s disease or ulcerative colitis. The study focuses ...


Breast, Colon, Esophagus, Kidney, Lip, Oral Cavity and Pharynx, Liver ...

Teva, TV56278-ONC-10203, Ph1a/1b, Open Label, Locally Adv or Metastatic Solid Tumors, TEV-56278

Objectives Primary To characterize the safety and tolerability of TEV-56278 in the trial population To determine a RP2D Secondary To characterize the serum pharmacokinetics of TEV-56278 in the trial population To evaluate the antitumor activity of ...


Breast, Cervix, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Corbus, CRB-601-01, PhI/II, open-label, various solid tumors, CRB-601

Primary Objective: Part A: To evaluate the safety and tolerability and determine the MTD and PADR for CRB-601 administered as a monotherapy in patients with select relapsed/refractory solid tumors who have progressed after at least one ...


Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...