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372 results found


Leukemia, other

Venetoclax and HMA-based Therapies for Adults With FLT3-mutated Acute Myeloid Leukemia: A MyeloMATCH Treatment Trial

This study focuses on adults diagnosed with acute myeloid leukemia (AML) who have previously participated in another study called the myeloMATCH study. The purpose of this research is to compare the usual drug combination treatment ...


Esophagus, Stomach

Nivolumab + Paclitaxel + Ramucirumab in Advanced Gastric and Esophageal Adenocarcinoma

This study focuses on people who have advanced stomach or esophageal cancer that has spread. The purpose of the study is to compare the usual treatment alone (the combination of 2 drugs, paclitaxel and ramucirumab) ...


Other

Efgartigimod in Kidney Transplant Recipients With Antibody-Mediated Rejection

The goal of this study is to evaluate the safety and effectiveness of an experimental drug called efgartigimod and how it affects kidney rejection in kidney transplant patients diagnosed with antibody-mediated rejection (AMR). AMR develops ...


Other

Long-term Safety and Efficacy of Tulisokibart in Crohn’s Disease or Ulcerative Colitis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) compared with placebo (inactive substance) in people with Crohn’s disease or ulcerative colitis. The study focuses ...


Breast, Colon, Esophagus, Kidney, Lip, Oral Cavity and Pharynx, Liver ...

Teva, TV56278-ONC-10203, Ph1a/1b, Open Label, Locally Adv or Metastatic Solid Tumors, TEV-56278

Objectives Primary To characterize the safety and tolerability of TEV-56278 in the trial population To determine a RP2D Secondary To characterize the serum pharmacokinetics of TEV-56278 in the trial population To evaluate the antitumor activity of ...