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KPL-387 Treatment in Recurrent Pericarditis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called KPL-387 for the treatment of recurrent pericarditis. Pericarditis is inflammation of the pericardium, which consists of 2 thin ...


Breast

RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for HR+/HER2- Metastatic Breast Cancer

This study focuses on people who have metastatic (spread to other areas of the body) hormone receptor-positive, human epidermal growth factor 2-negative (HR+/HER2-) breast cancer that has a mutation in a gene called PIK3CA. The ...


Other

Torque Teno Virus and Clinical Outcomes in Pediatric Kidney Transplant

This study focuses on children and teens (under 18 years old) who have received or are expected to receive a primary (first), kidney-alone transplant and who have been prescribed certain immunosuppression medications for their transplant. ...


Other

Debio 4126 in Patients With Acromegaly

This study focuses on people who have been diagnosed with acromegaly and have been receiving octreotide or lanreotide, and whose insulin-like growth factor 1 ( IGF-1) level is normal. Acromegaly is characterized by high IGF-1 ...


Other

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

The purpose of this study is to determine the safety and effectiveness of an experimental drug called orticumab for the treatment of coronary inflammation in people with prior myocardial infarction (heart attack) who have elevated ...