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RNIB21 in the Treatment of Irritable Bowel Syndrome with Diarrhea

The purpose of this study is to determine whether an investigational drug called RNIB21 can effectively relieve the symptoms of patients with irritable bowel syndrome with diarrhea (IBS-D). RNIB21 is a capsule that combines an ...


Lymphoid Leukemia

P-CD19CD20-ALLO1 in Subjects with Selected Relapsed/Refractory B Cell Malignancies

This study focuses on people who have a B cell malignancy that has returned after responding to previous treatment (relapsed) or is not responding to treatment (refractory). The purpose of the study is to determine ...


Unknown Sites

Doxorubicin + Pembrolizumab Versus Doxorubicin Alone in Undifferentiated Pleomorphic Sarcoma and Related Poorly Differentiated Sarcomas

The purpose of this study is to determine whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy (doxorubicin) can help patients with certain types of sarcoma (cancer) live longer without having disease progression. Participants will ...


Other

Bemnifosbuvir-Ruzasvir Versus Sofosbuvir-Velpatasvir in Chronic Hepatitis C Virus Infection

The purpose of this study is to compare the safety and effectiveness of an experimental drug called bemnifosbuvir-ruzasvir (BEM/RZR) to another drug, sofosbuvir/velpatasvir (SOF/VEL), in treating chronic hepatitis C virus (HCV) infection. The study focuses ...


Pancreas

Physical Activity Using Digital Health Technology in Adults With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

This study focuses on adults who have pancreatic cancer that has spread and caused unintentional weight loss. The purpose of the study is to evaluate whether a wearable device can be used to measure physical ...