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435 results found


Melanoma

Community-Based Strategies for Early Detection of Melanoma

The purpose of this study is to evaluate whether community education and digital skin screening tools can help improve early detection of melanoma when it is most treatable. Eligible participants may include melanoma survivors or ...


Colon, Rectum

Ivonescimab With FOLFOX Versus Bevacizumab With FOLFOX in Metastatic Colorectal Cancer

This study focuses on people with metastatic colorectal cancer. The purpose of the study is to evaluate the safety and effectiveness of an experimental drug called ivonescimab/SMT112 in combination with chemotherapy drugs (FOLFOX- oxaliplatin, leucovorin, ...


Other

BELIEVERS

The novelty of the BELIEVERS trial lies in being the first adequately powered, randomized study to compare TAVR and SAVR with a bioprosthesis in BAV, incorporating imaging-guided stratification to optimize outcomes, incorporating robust patient-engagement approach ...


Lung

HLX43 (Anti-PD-L1 ADC) in Advanced Non-Small Cell Lung Cancer

The purpose of this study is to determine the safety and effectiveness of an experimental drug called HLX43 for the treatment of advanced non-small cell lung cancer (NSCLC). Study procedures include administration of HLX43, questionnaires, ...


Other

EXPAREL Compared to Local Infiltration Analgesia in Primary Unilateral Total Knee Arthroplasty

This study focuses on people who are planning to receive a total knee arthroplasty (TKA, a surgical procedure also known as total knee replacement) in one of their knees. The purpose of the study is ...