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379 results found


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...


Other

JenaValve vs surgery ARTIST

To demonstrate non-inferiority of the Trilogy Transcatheter Heart Valve (THV) System compared with surgical aortic valve replacement (SAVR) for treatment of subjects with clinically significant native aortic regurgitation (AR)


Colon, Lung, Melanoma, Other Female Genital, Thyroid, Unknown Sites

KIN-2787 in Participants With BRAF and/or NRAS Mutation-Positive Solid Tumors

This early-phase clinical trial is designed for adults with advanced solid tumors that have spread (metastasized) and carry specific genetic mutations in the BRAF and/or NRAS genes—both of which are known to drive cancer progression. ...


Unknown Sites

Neoadjuvant Immunotherapy With Response-Adapted Treatment in Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma

This study focuses on people who have advanced squamous cell skin cancer that can be removed with surgery. The purpose of the study is to determine whether giving an immunotherapy drug called cemiplimab before and ...


Other

Using Circulating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-Associated Oropharyngeal Cancer

The purpose of this study is to determine whether using less intense radiation therapy and chemotherapy (chemoradiation) after trans-oral robotic surgery (TORS) will be as effective in treating HPV-associated oropharyngeal cancer as standard treatment while ...