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430 results found


ATTR-CM, Cardiac amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...


Amyotrophic lateral sclerosis (ALS)

The HEALEY ALS Platform Trial

The purpose of the HEALEY ALS Platform Trial is to evaluate the safety and effectiveness of multiple treatments for amyotrophic lateral sclerosis (ALS). A regimen is a specific course of treatment, each with a different ...


Acute pancreatitis, Pancreatitis

SHARP

This study focuses on patients who have been diagnosed with pancreas divisum and have had at least 2 episodes of pancreatitis. The purpose of the study is to determine whether endoscopic retrograde cholangiopancreatography (ERCP) with ...


Pancreas

Pancreatic Cancer Screening Program

The purpose of the study is to establish a pancreatic ductal adenocarcinoma (PDAC) screening program that collects the demographic and clinical information of patients and to study risk factors for progression to pancreatic ductal adenocarcinoma ...


Women's Heart Disease

Myocardial Steatosis in Women With Coronary Microvascular Dysfunction

This study focuses on women with angina (chest pain) who have been diagnosed with coronary microvascular dysfunction (CMD, abnormal function of the small microvessels within the heart). The purpose of the study is to understand ...