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438 results found


Kidney

Stereotactic Ablative Radiation Therapy for Metastatic Unresected Renal Cell Carcinoma Receiving Immunotherapy

This study focuses on people who have renal cell cancer that has spread beyond the kidney and for whom surgery is not currently recommended (or who have chosen not to have surgery). The study aims ...


Other

Beta 3 Enhanced Autonomic Therapy for POTS (BEAT-POTS)

The purpose of this study is to examine whether a drug called mirabegron reduces symptom frequency and improves quality of life in participants with postural orthostatic tachycardia syndrome (POTS). POTS is a condition in which ...


Pancreas

Expanded Access Program to Treat Patients with Previously Treated Metastatic Pancreatic Adenocarcinoma With Daraxonrasib

The purpose of this expanded access program (EAP), also known as “compassionate use,” is to provide access to an experimental medicine called daraxonrasib (RMC-6236) for patients who have been diagnosed with metastatic pancreatic adenocarcinoma. The ...


Other

Transcatheter Tricuspid Valve Replacement Using the Medtronic Intrepid TTVR System- PATHFINDER

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the Medtronic Intrepid TTVR system in patients with severe symptomatic tricuspid valve regurgitation whose doctor has recommended that ...


Colon, Lung, Pancreas, Rectum

KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

This study focuses on people who have an advanced or metastatic cancer that has a Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation that either has not responded to standard treatment, is unlikely to respond ...