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Xaluritamig in Relapsed or Refractory Ewing Sarcoma

The purpose of this study is to learn more about how treatment with an experimental drug called xaluritamig works in children, adolescents and young adults with Ewing sarcoma (EWS) that has come back after treatment ...


Brain and Nervous System

Black Diamond Therapeutics, BDTX-1535-201, Ph 2, Randomized, Glioblastoma, Silevertinib

Primary Objective: To compare the PFS of patients with newly diagnosed GBM with unmethylated MGMT promoter and EGFRvIII treated with silevertinib and TMZ or TMZ alone, administered as maintenance therapy post-adjuvant chemoradiation. Secondary Objectives: To compare ...