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165 results found


Brain and Nervous System

SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas

This study aims to determine whether tumor genetic testing would be helpful in guiding treatment for patients with a meningioma that has gotten bigger or grown back after treatment. Meningiomas are tumors that grow on ...


Breast

Shorter Anthracycline-Free Chemo Immunotherapy in Early Triple-Negative Breast Cancer

The purpose of this study is to compare the standard-of-care chemo-immunotherapy (carboplatin/paclitaxel followed by adriamycin/cyclophosphamide plus pembrolizumab, given in 6 months) treatment for early-stage, triple-negative breast cancer to a shorter non-anthracycline chemo-immunotherapy treatment (carboplatin docetaxel ...


Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female ...

GIM-122 as a Single Agent in Advanced Solid Malignancies

The purpose of this study is to evaluate an investigational drug called GIM-122 in people who have been diagnosed with an advanced or malignant tumors. These patients have tumors that were eligible to be treated ...


Colon, Rectum

Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery

This study focuses on individuals who have advanced colorectal cancer that has spread up to 4 body sites. The purpose of the study is to compare the usual treatment alone to ablative local therapy (ALT) ...


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...