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NPH, CAPPN

Enroll an inclusive cohort of approximately 10,000 diverse individuals from the All of Us Research Program that is representative of the U.S. population, heterogeneous in demographics, clinical characteristics, health parameters, and disease risk ...


Breast

Reinvigorating TNBC Response to Immunotherapy With Myeloid Inhibition and Radiation

The purpose of this study is to examine the feasibility, safety, and effectiveness of an experimental combination therapy of the drug axatilimab, radiation to the tumor, and pembrolizumab (another drug) in patients who have been ...


Pancreas

A Supervised Prehabilitation Program for Patients with Pancreatic Cancer

The purpose of this study is to evaluate the effects of a supervised prehabilitation exercise program in people with pancreatic cancer. Prehabilitation, or exercise prior to undergoing surgery or while concurrently undergoing treatment for cancer, ...


Melanoma

Sarilumab Combined With Ipilimumab, Nivolumab, and Relatlimab in Advanced/Unresectable Melanoma

This study will evaluate the safety and tolerability of a drug called sarilumab in combination with ipilimumab, nivolumab, and relatlimab in advanced/unresectable melanoma (melanoma that cannot be removed by surgery). Ipilimumab, nivolumab, and relatlimab ...


Prostate

Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

This study will evaluate an experimental drug called carotuximab when taken in combination with apalutamide, in comparison to apalutamide alone, for the treatment of metastatic, castration-resistant prostate cancer. Carotuximab is a genetically engineered antibody (type ...