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160 results found


Breast, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Nenocorilant in Combination With Anti-Programmed Cell Death/(Ligand) 1 in Solid Tumors

When cancers develop resistance to immunotherapy, tumors subsequently begin to grow. Cancer may use cortisol, a steroid hormone naturally produced in the body, to develop resistance to immunotherapy. Nenocorilant blocks the action of cortisol ...


Melanoma

CSMC, IIT2020-27-HAILE-WIPEOUT, Melanoma, Early Detection

-Assess the feasibility of the proposed behavioral intervention in low income and Latinx participants; -Extend the proposed intervention to family members and friends of participants; -Generate pilot feasibility data for an anticipated R01 grant application.


Colon, Rectum

Ivonescimab With FOLFOX Versus Bevacizumab With FOLFOX in Metastatic Colorectal Cancer

This study focuses on people with metastatic colorectal cancer. The purpose of the study is to evaluate the safety and effectiveness of an experimental drug called ivonescimab/SMT112 in combination with chemotherapy drugs (FOLFOX- oxaliplatin, leucovorin, ...


Lung

HLX43 (Anti-PD-L1 ADC) in Advanced Non-Small Cell Lung Cancer

The purpose of this study is to determine the safety and effectiveness of an experimental drug called HLX43 for the treatment of advanced non-small cell lung cancer (NSCLC). Study procedures include administration of HLX43, questionnaires, ...


Breast, Cervix, Lung, Other Female Genital, Ovary

SNV4818 as Monotherapy or in Combination With Other Anticancer Agents

The purpose of this study is to evaluate different drug doses of an experimental drug called SNV4818 and identify safe levels in patients with an advanced cancer that has a mutation (change) in their PIK3CA ...