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161 results found


Breast

Shortened Duration of Adjuvant Therapy in Early-Stage HER2+ Breast Cancer

This study focuses on people who have been diagnosed with HER2-positive (HER2+) breast cancer and have recently completed chemotherapy in combination with a drug called trastuzumab, followed by breast surgery. The chemotherapy plus trastuzumab produced ...


Breast, Larynx, Lung, Other Urinary

AVZO-1418 in Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called AVZO-1418 for the treatment of locally advanced solid tumors (cancers that have grown to a serious stage and ...


Breast, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Nenocorilant in Combination With Anti-Programmed Cell Death/(Ligand) 1 in Solid Tumors

When cancers develop resistance to immunotherapy, tumors subsequently begin to grow. Cancer may use cortisol, a steroid hormone naturally produced in the body, to develop resistance to immunotherapy. Nenocorilant blocks the action of cortisol ...


Melanoma

CSMC, IIT2020-27-HAILE-WIPEOUT, Melanoma, Early Detection

-Assess the feasibility of the proposed behavioral intervention in low income and Latinx participants; -Extend the proposed intervention to family members and friends of participants; -Generate pilot feasibility data for an anticipated R01 grant application.


Colon, Rectum

Ivonescimab With FOLFOX Versus Bevacizumab With FOLFOX in Metastatic Colorectal Cancer

This study focuses on people with metastatic colorectal cancer. The purpose of the study is to evaluate the safety and effectiveness of an experimental drug called ivonescimab/SMT112 in combination with chemotherapy drugs (FOLFOX- oxaliplatin, leucovorin, ...