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157 results found


Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...


Unknown Sites

COG, AOST2032, Ph 2/3, randomized, osteosarcoma, Cabozantinib + Cytotoxic Chemo

Primary Aims 1.1.1 To determine the feasibility of adding cabozantinib to standard MAP (high dose methotrexate, doxorubicin, and cisplatin) chemotherapy in patients with newly diagnosed metastatic osteosarcoma with a resectable primary tumor. 1.1.2 To determine whether MAP ...