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165 results found


Prostate

High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following ARPI Therapy

This study focuses on people who have a diagnosis of prostate cancer and are being treated with androgen receptor pathway inhibitor (ARPI) therapy. The purpose of the study is to determine whether there is a ...


Cervix, Lung, Melanoma, Other Urinary, Stomach, Unknown Sites

STK-012 as a Single Agent and in Combination Therapy in Advanced NSCLC

The purpose of this study is to measure how well an experimental drug called STK-012 works in combination with the drugs pembrolizumab, pemetrexed and carboplatin for the treatment of advanced non-small cell lung cancer. STK-012 ...


Prostate

Pasritamig + Best Supportive Care Versus Best Supportive Care for Metastatic Castration-Resistant Prostate Cancer

The purpose of this study is to learn whether an experimental immunotherapy called pasritamig added to best supportive care (including radiation, steroids, pain medication, or medications to strengthen the bones) for metastatic castration-resistant prostate cancer ...


Pancreas

ASP3082 in Combination With mFOLFIRINOX or NALIRIFOX in KRAS G12D-Mutated Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ASP3082 in people who have metastatic pancreatic ductal adenocarcinoma cancer (PDAC) with a KRAS G12D mutation when combined ...


Pancreas

Daraxonrasib Vs. Standard-of-Care Observation in Resected Pancreatic Ductal Adenocarcinoma

The purpose of this study is to evaluate the safety, tolerability and effectiveness of an experimental drug called daraxonrasib (RMC-6236) in people with pancreatic cancer compared to standard-of-care treatment. Patients will be randomly assigned to ...