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164 results found


Cervix

HPV and Post-Treatment Surveillance

The purpose of this study is to examine the association between high-risk human papillomavirus (hr-HPV) with cancer recurrence among women who have completed treatment for invasive cervical cancer. Participants will be asked to complete a ...


Non-Hodgkin Lymphoma

Alliance, A051902, Phase II, OL, T-cell Lymphomas, CHO(E)P vs CC-486- CHO(E)P vs duvelisib-CHO(E)P

Primary objective: To compare the complete remission (CR) rates by FDG PET/CT using the Lugano 2014 criteria following completion of treatment with duvelisib-CHO(E)P vs CHO(E)P and with CC-486-CHO(E)P vs CHO(E)P in previously untreated peripheral ...


Colon

Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer

The purpose of this study is to evaluate the effectiveness and safety of specially selected, multiple therapies in patients with metastatic colorectal cancer (mCRC). The study will evaluate the effects of an experimental drug called ...


Prostate

NRG, NRG-GU010, Ph 3, Open Label, Prostate, RT vs. RT + ADT vs. RT + ADT + Darolutamide

1.1 Primary Objectives: 1.1.1 De-Intensification Study: To determine whether men with National Comprehensive Cancer Network (NCCN) unfavorable intermediate risk (UIR) prostate cancer and lower Decipher genomic risk (Decipher score < 0.40) treated with RT alone instead of ...


Breast, Colon, Esophagus, Kidney, Lung, Melanoma, Ovary

Shionogi, 2023P2411(aCCeleR8-001), Ph1b/2,Open,Advanced Solid Tumors,S-531011 +/- Pembrolizumab

Primary: -To evaluate the safety and tolerability of S-531011 and to determine the MTD and/or RP2D of S-531011. Secondary: - To evaluate the preliminary antitumor activity of S-531011 per RECIST version 1.1a. - To characterize the PK profile ...