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160 results found


Brain and Nervous System

Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

The purpose of the study is to determine whether an investigational drug called pembrolizumab combined with standard-of-care stereotactic radiation therapy and surgery is safe and effective in patients with recurrent glioblastoma. Researchers will evaluate whether ...


Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...


Cervix

HPV and Post-Treatment Surveillance

The purpose of this study is to examine the association between high-risk human papillomavirus (hr-HPV) with cancer recurrence among women who have completed treatment for invasive cervical cancer. Participants will be asked to complete a ...


Non-Hodgkin Lymphoma

Alliance, A051902, Phase II, OL, T-cell Lymphomas, CHO(E)P vs CC-486- CHO(E)P vs duvelisib-CHO(E)P

Primary objective: To compare the complete remission (CR) rates by FDG PET/CT using the Lugano 2014 criteria following completion of treatment with duvelisib-CHO(E)P vs CHO(E)P and with CC-486-CHO(E)P vs CHO(E)P in previously untreated peripheral ...


Colon

Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer

The purpose of this study is to evaluate the effectiveness and safety of specially selected, multiple therapies in patients with metastatic colorectal cancer (mCRC). The study will evaluate the effects of an experimental drug called ...