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149 results found

Gastrointestinal Cancer, Liver Cancer

Microbial Biomarkers for Hepatocellular Carcinoma

This study focuses on patients who are about to begin treatment for advanced liver cancer at Cedars-Sinai. The purpose of the study is to determine how bacteria in the digestive tract could contribute to response ...

Bladder cancer, Urology

Concurrent Chemoradiotherapy with or Without Atezolizumab in Localized Muscle Invasive Bladder Cancer

The purpose of this study is to compare the effects of chemotherapy and radiation therapy with or without the use of an immunotherapy drug called atezolizumab, which is used to treat bladder cancer. Participants will ...

Melanoma, Other Skin, Other Urinary, Ovary, Unknown Sites

IMC-F106C in Advanced Cancers

The purpose of this study is to determine the safety and effectiveness of an investigational immunotherapeutic drug called IMC-F106C in multiple cancers (endometrial, ovarian, melanoma, ocular melanoma, triple-negative breast, lung, and bladder cancer) expressing a ...

Leukemia, not otherwise specified

Inotuzumab Ozogamicin for Newly Diagnosed High-Risk B-ALL

This study focuses on individuals who have been diagnosed with mixed-phenotype acute leukemia (MPAL). MPAL is a cancer of the white blood cells that occurs in the bone marrow and is a rare form of ...

Melanoma, Soft Tissue

Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Melanoma

Substudies 02A, 02B, and 02C: To assess the safety and tolerability of investigational treatment combinations based on the proportion of participants with adverse events (AEs). Substudies 02A and 02B: To evaluate objective response rate (ORR) as assessed ...