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141 results found


Pancreatic Cancer

Perioperative Versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer

The purpose of this study is to compare the usual treatment approach (surgery followed by chemotherapy) to using chemotherapy followed by surgery and then more chemotherapy in people with removable pancreatic cancer. The addition of ...


Melanoma

Early Discontinuation of Anti-PD-1 Therapy in Patients With Advanced Melanoma

This study focuses on individuals who have advanced melanoma cancer that is currently being treated with one immunotherapy drug (anti-PD-1 drugs nivolumab or pembrolizumab) or a combination of nivolumab and ipilimumab. Researchers aim to determine ...


Kidney

Immunotherapy-Based Combination Therapy With Or Without Cytoreductive Nephrectomy

This study focuses on individuals who have newly diagnosed kidney cancer that has spread outside of the kidney (metastatic kidney cancer) and who have not started therapy or just recently started their first therapy. Patients ...


Larynx, Lip, Oral Cavity and Pharynx

Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Cancer of the Head and Neck

The purpose of this study is to determine whether post-operative radiation therapy with the drugs docetaxel and cetuximab, or post-operative radiation therapy with cisplatin and an immunotherapy drug, atezolizumab, is better than the usual approach ...


Breast, Rectum

CSMC, IIT2020-26-FIGUEIREDO-TRE, cancer, time-restricted eating

This research will answer three key questions: (1) can TRE improve clinical outcomes, including treatment toxicity, patient-reported outcomes, and tumor regression (Aim 1) (2) do the underlying molecular mechanisms support the Differential Stress Sensitization theory ...