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161 results found


Breast, Rectum

CSMC, IIT2020-26-FIGUEIREDO-TRE, cancer, time-restricted eating

This research will answer three key questions: (1) can TRE improve clinical outcomes, including treatment toxicity, patient-reported outcomes, and tumor regression (Aim 1) (2) do the underlying molecular mechanisms support the Differential Stress Sensitization theory ...


Brain and Nervous System

Platform Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

The purpose of the study is to evaluate multiple experimental treatments for either newly diagnosed or recurrent brain cancer (glioblastoma) to determine whether any of these treatments improve how long patients live compared to standard-of-care ...


Gastrointestinal Cancer, Liver Cancer

CSMC, IIT2020-04-Hussain-HCCBIO, Pilot, Imaging Biomarkers Bank, Hepatocellular Carcinoma

The purpose of the research is to identify histopathological features and blood biomarkers that correlate with imaging biomarkers.


Other Endocrine System, Pancreas

Merck, MK-6482-015, Ph 2, Open-label, PPGL & pNET, MK6482 Monotherapy

The purpose of this study is to evaluate the investigational use of a drug called belzutifan (MK-6482) in people with certain types of pheochromocytoma/ paraganglioma (PPGL) and pancreatic neuroendocrine tumors (pNET). The study will examine ...


Brain and Nervous System

Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

The purpose of the study is to determine whether an investigational drug called pembrolizumab combined with standard-of-care stereotactic radiation therapy and surgery is safe and effective in patients with recurrent glioblastoma. Researchers will evaluate whether ...