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MK-7240 in Moderately to Severely Active Ulcerative Colitis

The purpose of this research is to evaluate the safety and effectiveness of an experimental drug called MK-7240 (tulisokibart) compared with placebo (inactive substance) in people with moderately to severely active ulcerative colitis. There are ...


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Tulisokibart in Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) in people with moderately to severely active Crohn’s disease that has not responded well to treatment. ...


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Etrasimod’s Effects on Vascular Pathobiology Using IUS: A Potential Marker of Early Response in Ulcerative Colitis

This study focuses on people with ulcerative colitis (an inflammatory disease of the bowel) who are starting a drug called etrasimod as standard of care. The study aims to show that etrasimod reduces abnormal blood ...


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Seladelpar in Primary Biliary Cholangitis and Compensated Cirrhosis

The purpose of this study is to determine whether an experimental drug called seladelpar is effective in improving outcomes for people with primary biliary cholangitis (PBC) and compensated cirrhosis. PBC is a chronic liver disease ...


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Olympus_HANAROSTENT Biliary Flap Lasso Stent System IDE Study

The study objective is to demonstrate clinical performance and safety of the fully covered (FC) HANAROSTENT® Biliary Flap Lasso Stent System with anti-migration flaps for the palliative treatment of malignant biliary obstruction.