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Transcutaneous ultrasound and eosinophilic esophagitis

The aims of this study are to 1) assess esophagus measurements in patients with and without EoE, 2) correlate esophagus measurements with eosinophil counts noted on histology, and 3) assess changes in esophageal measurements over ...


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VS-01 in Acute-On-Chronic Liver Failure

The purpose of this study is to determine whether an investigational drug called VS-01 will help in the treatment of acute-on-chronic liver failure (ACLF) grades 1 and 2 with fluid in the abdomen (ascites). ACLF ...


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Dual Targeted Therapy in Moderate to Severe Crohn's Disease

The purpose of this study is to determine whether combining approved treatments (dual therapy) for Crohn’s disease is safe and improves patient outcomes. The treatment combinations referred to as “dual targeted therapy” are vedolizumab given ...


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Vedolizumab-4054 UC

To determine the effect of dual targeted therapy with an anti-integrin (vedolizumab [VDZ]) and a Janus kinase (JAK) inhibitor (tofacitinib [TOF]) on clinical remission.


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Hepatocyte Transplantation Into Periduodenal Lymph Nodes in End-Stage Liver Disease

The purpose of this study is to evaluate an experimental treatment called allogeneic hepatocyte transplantation (injection of donor liver cells) as a possible treatment for end-stage liver disease (ESLD). The study aims to identify the ...