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Pegozafermin in Metabolic Dysfunction-Associated Steatohepatitis and Fibrosis

This study focuses on people who may have metabolic dysfunction-associated steatohepatitis (MASH), also called nonalcoholic steatohepatitis, that will be confirmed by a biopsy. The purpose of the study is to learn about the safety and ...


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Pegozafermin in Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatohepatitis

The purpose of this study is to learn about the safety, effectiveness, and long-term outcomes of an experimental drug called pegozafermin in people with compensated cirrhosis (advanced scarring of the liver) due to metabolic dysfunction-associated ...


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RNIB21 in the Treatment of Irritable Bowel Syndrome with Diarrhea

The purpose of this study is to determine whether an investigational drug called RNIB21 can effectively relieve the symptoms of patients with irritable bowel syndrome with diarrhea (IBS-D). RNIB21 is a capsule that combines an ...


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Bemnifosbuvir-Ruzasvir Versus Sofosbuvir-Velpatasvir in Chronic Hepatitis C Virus Infection

The purpose of this study is to compare the safety and effectiveness of an experimental drug called bemnifosbuvir-ruzasvir (BEM/RZR) to another drug, sofosbuvir/velpatasvir (SOF/VEL), in treating chronic hepatitis C virus (HCV) infection. The study focuses ...


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GSK4532990 for Steatohepatitis in Adults With Alcohol-related Liver Disease

The purpose of this study is to evaluate the safety and effects of an experimental drug called GSK4532990 on steatohepatitis (fatty liver disease) in adults with alcohol-related liver disease (ALD), a condition in which there ...