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29 results found


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Hepatocyte Transplantation Into Periduodenal Lymph Nodes in End-Stage Liver Disease

The purpose of this study is to evaluate an experimental treatment called allogeneic hepatocyte transplantation (injection of donor liver cells) as a possible treatment for end-stage liver disease (ESLD). The study aims to identify the ...


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Phase II Study of Unresectable Hepatocellular Carcinoma and Cirrhosis

The purpose of this study is to evaluate the effects of combined immunotherapy regimens (atezolizumab with bevacizumab) in patients with inoperable liver cancer and liver disease (cirrhosis). Participants may receive atezolizumab alone (if they are ...


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Merck_MK-7240-001

To evaluate the efficacy of MK-7240 compared to Placebo as assessed by the proportion of participants achieving clinical remission per Modified Mayo Score at Week 12 and at Week 52. To evaluate the safety ...


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Tulisokibart in Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) in people with moderately to severely active Crohn’s disease that has not responded well to treatment. ...


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CymaBay Therapeutics_CB8025-41837_AFFIRM

To evaluate the effect of seladelpar compared to placebo on event free survival (EFS).