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29 results found


Liver cirrhosis, Portal hypertension

Zibotentan and Dapagliflozin, and Dapagliflozin Monotherapy in Cirrhosis

The purpose of this study is to learn more about the effects of 2 drugs, zibotentan and dapagliflozin, in people with liver disease (cirrhosis) with features of increased pressure in portal veins (portal hypertension). The ...


Other

Guselkumab and Golimumab in Ulcerative Colitis

The purpose of this study is to determine whether the experimental combination of guselkumab and golimumab is safe and effective for treating patients with moderately to severely active ulcerative colitis. Treatment with three different doses ...


Crohn's disease [regional enteritis]

Guselkumab and Golimumab in Crohn’s Disease

The purpose of this study is to determine whether the investigational combination of 2 drugs, guselkumab and golimumab, is safe and effective for treating patients with moderately to severely active Crohn’s disease. 3 different doses ...


Other

Auxora in Acute Pancreatitis and Accompanying Systemic Inflammatory Response Syndrome

The purpose of this study is to determine whether an experimental drug called Auxora is safe to use in people who have acute pancreatitis with accompanying systemic inflammatory response syndrome (SIRS). Acute pancreatitis with SIRS ...


Other

Versantis_GENFIT_UNVEIL-IT

8.1. PRIMARY OBJECTIVE 1. To evaluate the efficacy of VS-01 administered i.p. daily over 4 days on top of SOC vs. SOC alone in patients with ACLF grades 1 and 2 as measured by CLIF-C ACLF ...