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The purpose of this study is to evaluate the investigational use of a drug called volixibat for the treatment of pruritis (itching) associated with primary sclerosing cholangitis (PSC). In the first part of the study ...

Pancreatic Biliary Diseases, Pancreatic Cancer

MRI to Predict Outcomes of PDAC

This study focuses on patients who are receiving care for non-metastatic pancreatic cancer at Cedars-Sinai. The purpose of the study is to evaluate the role of a method of magnetic resonance imaging (MRI) analysis for ...


Induction Therapy with PRA023 in Ulcerative Colitis

This study focuses on individuals with ulcerative colitis (UC) that has been assessed as being moderate to severe. The purpose of the study is to determine whether an investigational drug called PRA023 is safe and ...


Exact Science, ALTUS2021-01, at Risk for Hepatocellular Ca (HCC), Multi-Target Test Oncoguard

Primary Objective: Assess overall sensitivity and specificity of Oncoguard Liver for hepatocellular cancer (HCC) detection in a surveillance population. Secondary Objective(s): Assess performance of Oncoguard Liver in confirmed HCC and non-HCC population. Assess early-stage sensitivity of Oncoguard Liver ...


Global Linerixibat Itch STudy of Efficacy and Safety iN PBC (GLISTEN)

Cholestatic pruritus burdens up to three quarters of patients with PBC during the course of their disease. This itch due to this rare and chronic liver disease, represents a serious condition that continues to lack effective treatments. Linerixibat, ...