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38 results found


Ulcerative colitis

Guselkumab and Golimumab in Ulcerative Colitis

The purpose of this study is to determine whether the experimental combination of guselkumab and golimumab is safe and effective for treating patients with moderately to severely active ulcerative colitis. Treatment with three different doses ...


Other

Auxora in Acute Pancreatitis and Accompanying Systemic Inflammatory Response Syndrome

The purpose of this study is to determine whether an experimental drug called Auxora is safe to use in people who have acute pancreatitis with accompanying systemic inflammatory response syndrome (SIRS). Acute pancreatitis with SIRS ...


Other

ELUXEO Vision Endoscopic Assessment of Tissue Oxygen Saturation

The purpose of this study is to examine gastrointestinal organs and tissues with an endoscopic device called ELUXEO Vision, which measures real-time oxygen levels in the tissue and is approved by the U.S. Food and ...


Other

Simvastatin Treatment to Improve Patient-Reported Outcomes in Chronic Pancreatitis

The purpose of this pilot study is to evaluate a drug called simvastatin for potential treatment of adults with recurrent acute pancreatitis or chronic pancreatitis. Participants will receive simvastatin or placebo (inactive substance); they will ...


Crohn's disease [regional enteritis]

Dual Targeted Therapy in Moderate to Severe Crohn's Disease

The purpose of this study is to determine whether combining approved treatments (dual therapy) for Crohn’s disease is safe and improves patient outcomes. The treatment combinations referred to as “dual targeted therapy” are vedolizumab given ...