Find Clinical Trials | Cedars-Sinai

75 results found

Genetic Disorders of the Cardiovascular System, Heart failure

Cytokinetics (CK-3773274)

This study focuses on adults who have obstructive hypertrophic cardiomyopathy (oHCM), abnormally thick heart muscle, and left ventricular outflow tract (LVOT) obstruction (a condition which interferes with the flow of blood in the heart). The ...

Cardiac surgery

TRAVERSE: Transseptal vs Retrograde Aortic Ventricular Entry

The purpose of this study is to compare 2 methods that are each routinely performed as standards of care (a transseptal approach versus a retrograde approach) of performing a procedure, called ablation, to treat abnormal ...

ATTR-CM, Cardiac amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...

Women's Heart Disease

Myocardial Steatosis in Women With Coronary Microvascular Dysfunction

This study focuses on women with angina (chest pain) who have been diagnosed with coronary microvascular dysfunction (CMD, abnormal function of the small microvessels within the heart). The purpose of the study is to understand ...

Mitral Valve Regurgitation

SAPIEN M3 System TransCatheter Mitral Valve ReplaCement via Transseptal Access  

The purpose of this study is to examine the safety and effectiveness of the investigational SAPIEN M3 System, a mitral valave replacement system, in patients with blood backflow (mitral regurgitation) across the mitral valve. The ...