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MagicTouch Sirolimus-Coated Balloon in Coronary Artery Lesions of In-Stent Restenosis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug-coated balloon system called the MagicTouch sirolimus-coated balloon for the treatment of coronary in-stent restenosis (recurrence of narrowing of a ...


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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

The goal of this study is to identify the best way to treat pulmonary embolism (blood clots in the lungs), specifically when there is a large amount of clot, but the patient’s blood pressure is ...


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AltaValve Pivotal Trial Protocol

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the AltaValve System in people with moderate-to-severe and severe mitral regurgitation. The study aims to determine whether the ...


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Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy

This study focuses on people who have been diagnosed with obstructive hypertrophic cardiomyopathy (oHCM), a condition in which the heart muscle thickens and blocks blood flow from the heart. The purpose of the study is ...


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Long-Term Safety and Efficacy of NNC6019-0001 in Transthretin Amyloid Cardiomyopathy

The purpose of this study is to evaluate the long-term safety and effectiveness of a medicine called NNC6019-0001 in people who have heart failure due to transthyretin (TTR) amyloidosis (build-up of abnormal protein in heart ...