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49 results found

Women's Heart Disease

Myocardial Steatosis in Women With Coronary Microvascular Dysfunction

This study focuses on women with angina (chest pain) who have been diagnosed with coronary microvascular dysfunction (CMD, abnormal function of the small microvessels within the heart). The purpose of the study is to understand ...

Valvular Heart Disease

TRISCEND II Pivotal Trial

This study focuses on adults who have tricuspid regurgitation (TR), a condition in which the heart's tricuspid valve does not close tightly, causing blood to flow backwards in the wrong direction. The purpose of the ...


Optimizer Smart PAS

The MDAC panel recommended a post-approval study that evaluates data such as cardiac outcomes, quality of life, mortality, and functionality. Long term data are also needed to assess complication rates and potential interactions with other ...

Mitral Valve Regurgitation

SAPIEN M3 System TransCatheter Mitral Valve ReplaCement via Transseptal Access  

The purpose of this study is to examine the safety and effectiveness of the investigational SAPIEN M3 System, a mitral valave replacement system, in patients with blood backflow (mitral regurgitation) across the mitral valve. The ...

Valvular Heart Disease


The purpose of this study is to evaluate the safety and effectiveness of an investigational medical device called the MitraClip Mitral Valve Repair System (MitraClip System) in patients with severe primary mitral regurgitation who are ...