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27 results found


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Eliminating Post-Mastectomy Pain and Opioids With Percutaneous Cryoneurolysis

This study focuses on individuals who are scheduled for a mastectomy surgery that frequently results in moderate-to-severe pain. The purpose of the study is to determine whether temporarily freezing the nerves that go to the ...


Multiple Sclerosis

Lesion-Specific Mechanisms Driving Degeneration of the Visual Axis in Multiple Sclerosis

The purpose of this study is to evaluate the effects of multiple sclerosis (MS) lesions in the visual pathway and how they contribute to nerve cell loss in the retina and impact visual function over ...


Amyotrophic lateral sclerosis (ALS)

Identifying Upper Motor Neuron Pathology in ALS and Other Neurodegenerative Diseases With High-Resolution MRI

The purpose of the study is to evaluate the usefulness of a new style of brain imaging for patients with amyotrophic lateral sclerosis (ALS), variants of ALS, and other neurological disorders. This type of brain ...


Alzheimer's disease, Dementia, Memory, Mild cognitive impairment

Benfotiamine in Patients With Early Alzheimer’s Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called benfotiamine as a possible treatment for Alzheimer’s disease (AD). Benfotiamine is a lab-made version of vitamin B1 (thiamine). ...


Other

Intraoperative Assessment of Tissue With Time-Resolved Fluorescence Spectroscopy

The purpose of this study is to evaluate the use of a device in the detection of tumor tissue versus normal tissue at the time of surgery. The technique used by the device is called ...