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16 results found


Disease-free, Ovary

Health Care Outcomes Following Risk-Reducing Salpingo-Oophorectomy

The purpose of this study is to evaluate the long-term effect of risk-reducing, bilateral salpingo-oophorectomy (removal of fallopian tubes and ovaries) on health outcomes in women with genetic mutations known to increase the risk for ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Targeted Agent and Profiling Utilization Registry (TAPUR) Study

This study focuses on patients who have been diagnosed with an advanced cancer that has not responded to or has stopped responding to at least one kind of treatment, or that has no standard therapy. ...


Breast, Colon, Esophagus, Kidney, Other Digestive Organ, Other Female Genital ...

Identifying Cryptic Causes for High-Risk Hereditary Cancer Syndromes

Hereditary cancer syndromes are caused by germline mutations or epimutations (an epigenetic error that switches a gene off) within cancer-related genes. These mutations or epimutations confer a high risk of cancer development in individuals and ...


Other Female Genital, Other Male Genital, Ovary, Soft Tissue

Active Surveillance for Low Risk and Trial of Carboplatin vs. Cisplatin for Standard Risk Patients with Germ Cell Tumors

This study focuses on patients who have been diagnosed with a germ cell tumor (GCT). The “germ cell” is a cell that will become either the egg or the sperm. A germ cell tumor is ...


Melanoma, Other Skin, Other Urinary, Ovary, Unknown Sites

IMC-F106C in Advanced Cancers

The purpose of this study is to determine the safety and effectiveness of an investigational immunotherapeutic drug called IMC-F106C in multiple cancers (endometrial, ovarian, melanoma, ocular melanoma, triple-negative breast, lung, and bladder cancer) expressing a ...