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136 results found


Bladder cancer, Ovarian cancer, Uterine cancer

Acrivon Ther, ACR-368-201/GOG-3082,Ph1b/2,Open-label,Ovarian/endometrial/uroth,ACR-368+/-Gemcitabine

Primary Arm 1 Assess the anti-tumor activity of ACR-368 monotherapy in each cohort (ovarian, endometrial, urothelial) of OncoSignature Positive subjects. Arm 2 Assess the safety and tolerability of ACR-368 in combination with LDG Determine the RP2D of LDG Secondary Arm 1 Confirmation of ...


Lung

Non-Small Cell Lung Cancer: Lung-MAP Sub-Study

The purpose of this study is to determine whether a combination of drugs (capmatinib, osimertinib, and ramucirumab) is beneficial compared to another combination (capmatinib and osimertinib) for treating non-small cell lung cancer tumors that have ...


Ovary

Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer

This study aims to determine whether 2 surgical procedures are no different for ovarian cancer risk reduction in individuals with BRCA1 mutations who have completed childbearing. (Mutations in the BRCA1 gene are associated with a ...


Breast

Da Vinci SP Surgical System in Nipple-Sparing Mastectomy

The purpose of this clinical study is to collect data about the use of a robotic device called the da Vinci Single-Port (SP) Surgical System in nipple-sparing mastectomy (NSM) procedures. NSM is a surgery for ...


Lung, Rectum

HPN328 in Advanced Cancers Associated with DLL3

The purpose of this study is to test the safety and effects of an experimental drug called HPN328 alone and in combination with another drug, atezolizumab, in patients who have small cell lung cancer or ...