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161 results found


Prostate

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

The purpose of this study is to determine whether a commonly used cholesterol-lowering therapies can help recruit antitumor immune cells into a prostate tumor. The study focuses on people with prostate cancer who have elected ...


Kidney

HC-7366 in Combination With Belzutifan in Renal Cell Carcinoma

This study focuses on people with locally advanced or metastatic, clear cell renal cell carcinoma (a specific type of kidney cancer) who have gotten worse after treatment with at least 1 but no more than ...


Myeloid and Monocytic Leukemia

MYELOMATCH, Master Screening and Reassessment Protocol

In this study, researchers will plan various treatment substudies for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have not yet started treatment. Participants will be asked to undergo testing on their ...


Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...


Lung

LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in Non-Small Cell Lung Cancer

The purpose of this study is to determine whether the addition of an investigational drug called LY3537982 to the current standard-of-care treatment (immunotherapy +/- chemotherapy) helps control cancer for a longer period of time and ...