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155 results found


Prostate

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

The purpose of this study is to determine whether a commonly used cholesterol-lowering therapies can help recruit antitumor immune cells into a prostate tumor. The study focuses on people with prostate cancer who have elected ...


Non-Hodgkin's Lymphoma

IPH6501 in Relapsed and/or Refractory Non-Hodgkin Lymphoma

The purpose of this study is to determine the safety and tolerability of an experimental drug called IPH6501, as well as evaluate its activity against cancerous cells causing lymphoma. The study focuses on people who ...


Unknown Sites

Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers

The purpose of this study is to evaluate how the combination of the drugs nivolumab and relatlimab might work in people with advanced cancer that is “microsatellite instability high” (MSI-H). Microsatellite instability is a marker ...


Myeloid and Monocytic Leukemia

MYELOMATCH, Master Screening and Reassessment Protocol

In this study, researchers will plan various treatment substudies for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have not yet started treatment. Participants will be asked to undergo testing on their ...


Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...