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16 results found


Lung, Pulmonary Vascular Disease, Pulmonary hypertension

State of Energy in the Right Ventricle of Patients With PAH

The purpose of the study is to evaluate a technique to monitor disease progression or regression in patients with pulmonary arterial hypertension (PAH). PAH is indicated by high blood pressure in the pulmonary arteries. Right ...


Other

MYK-224 in Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

The purpose of this study is to examine the safety and effectiveness of an investigational drug called MYK-224 in individuals with obstructive hypertrophic cardiomyopathy (oHCM). The amount of MYK-224 that reaches the blood stream and ...


Amyotrophic lateral sclerosis (ALS)

Identifying Upper Motor Neuron Pathology in ALS and Other Neurodegenerative Diseases With High-Resolution MRI

The purpose of the study is to evaluate the usefulness of a new style of brain imaging for patients with amyotrophic lateral sclerosis (ALS), variants of ALS, and other neurological disorders. This type of brain ...


Other

Eplontersen in Transthyretin-Mediated Amyloid Cardiomyopathy

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called eplontersen in people with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM). ATTRCM is a disease caused by change in a protein ...


Pregnancy without an Associated Complication

The HEALthy Brain and Child Development (HBCD) Study

Leading researchers in the fields of child development and neuroscience will work with participating families and their children to learn how children develop early in life. This study will help us learn more about child development ...