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32 results found


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Tulisokibart in Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) in people with moderately to severely active Crohn’s disease that has not responded well to treatment. ...


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Etrasimod’s Effects on Vascular Pathobiology Using IUS: A Potential Marker of Early Response in Ulcerative Colitis

This study focuses on people with ulcerative colitis (an inflammatory disease of the bowel) who are starting a drug called etrasimod as standard of care. The study aims to show that etrasimod reduces abnormal blood ...


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Seladelpar in Primary Biliary Cholangitis and Compensated Cirrhosis

The purpose of this study is to determine whether an experimental drug called seladelpar is effective in improving outcomes for people with primary biliary cholangitis (PBC) and compensated cirrhosis. PBC is a chronic liver disease ...


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Biliary Stent with Anti-migration Flaps for the Palliative Treatment of Malignant Biliary Obstruction

The purpose of this study is to evaluate how an investigational device called the Hanarostent works to relieve obstructive symptoms in patients with cancer who have a blockage in their bile duct caused by cancer. ...


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Long-term Safety and Efficacy of Tulisokibart in Crohn’s Disease or Ulcerative Colitis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) compared with placebo (inactive substance) in people with Crohn’s disease or ulcerative colitis. The study focuses ...