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140 results found


Ovary

Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer

This study aims to determine whether 2 surgical procedures are no different for ovarian cancer risk reduction in individuals with BRCA1 mutations who have completed childbearing. (Mutations in the BRCA1 gene are associated with a ...


Brain and Nervous System

SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas

This study aims to determine whether tumor genetic testing would be helpful in guiding treatment for patients with a meningioma that has gotten bigger or grown back after treatment. Meningiomas are tumors that grow on ...


Multiple Myeloma

Low-Dose Palliative Radiotherapy in Bone Metastases from Multiple Myeloma

The purpose of this study is to evaluate whether pain relief can be achieved using only 1-2 radiation treatments to a painful bone lesion in patients with multiple myeloma (MM). Bone disease is common in ...


Breast

Da Vinci SP Surgical System in Nipple-Sparing Mastectomy

The purpose of this clinical study is to collect data about the use of a robotic device called the da Vinci Single-Port (SP) Surgical System in nipple-sparing mastectomy (NSM) procedures. NSM is a surgery for ...


Hodgkin's Lymphoma, Leukemia, not otherwise specified, Leukemia, other, Lymphoid Leukemia ...

Post-Transplant Cyclophosphamide

The purpose of this study is to determine the best dose of an immune suppressive drug, cyclophosphamide, following standard stem cell transplant in older patients (at least 65 years old). Participants will undergo a stem ...