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414 results found


Brain and Nervous System

COG, ANBL1531, Ph3, open label, high-risk Neuroblastoma, 131I-MIBG or Crizotinib

PRIMARY: - To determine in the context of a randomized trial whether the EFS of patients with newly diagnosed high-risk NBL is improved with the addition of 131I-MIBG during Induction, prior to tandem autologous stem cell ...


Inflammatory Bowel Disease

CORALE - IBD

This study focuses on individuals who are at least 13 years old and have inflammatory bowel disease (Crohn's disease or ulcerative colitis). The purpose of the study is to understand the effects of COVID-19 vaccination ...


Movement Disorders, Parkinson's Disease

Boundless

This study focuses on individuals who have Parkinson's disease with poorly controlled or involuntary movement symptoms. The purpose of the study is to evaluate the effectiveness and safety of an investigational drug called ND0612, delivered ...


Brain and Nervous System

Platform Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

The purpose of the study is to evaluate multiple experimental treatments for either newly diagnosed or recurrent brain cancer (glioblastoma) to determine whether any of these treatments improve how long patients live compared to standard-of-care ...


Pancreas

Prospective Registry of Shear Wave Elastography for the Pancreas Using Endoscopic Ultrasound

Primary objective: The primary objective is to obtain preliminary estimates of safety and feasibility of shear wave EUS. Safety will be evaluated by complications, if any, from the procedure. Shear wave is expected to ...