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387 results found


ATTR-CM, Cardiac amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...


Movement Disorders

ADROIT

This data collection study focuses on individuals who are scheduled to receive an Abbott Deep Brain Stimulation (DBS) systems implant to help treat their movement disorder. DBS therapy uses small electrical pulses at a specific ...


Amyotrophic lateral sclerosis (ALS)

The HEALEY ALS Platform Trial

The purpose of the HEALEY ALS Platform Trial is to evaluate the safety and effectiveness of multiple treatments for amyotrophic lateral sclerosis (ALS). A regimen is a specific course of treatment, each with a different ...


Orthopaedics

Infuse Bone Graft

This study focuses on individuals who have been diagnosed with degenerative disc disease at one or more levels of their spine and who have not responded to non-surgical treatments. The purpose of the study is ...


Acute pancreatitis, Pancreatitis

SHARP

This study focuses on patients who have been diagnosed with pancreas divisum and have had at least 2 episodes of pancreatitis. The purpose of the study is to determine whether endoscopic retrograde cholangiopancreatography (ERCP) with ...