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Biliary Stent with Anti-migration Flaps for the Palliative Treatment of Malignant Biliary Obstruction

The purpose of this study is to evaluate how an investigational device called the Hanarostent works to relieve obstructive symptoms in patients with cancer who have a blockage in their bile duct caused by cancer. ...


Lung

Subcutaneous Amivantamab With Lazertinib or Subcutaneous Amivantamab With Chemotherapy in EGFR-Mutated Non-Small Cell Lung Cancer

This study focuses on people with non-small cell lung cancer (NSCLC) who have a specific mutation in a gene called the epidermal growth factor receptor (EFGR) gene. The purpose of the study is to learn ...


Other

NTLA-2001 in Transthyretin Amyloidosis With Cardiomyopathy

The purpose of this study is to understand how an experimental drug called NTLA-2001 affects a heart condition called transthyretin (TTR) amyloidosis with cardiomyopathy (ATTR-CM), a condition in which the heart muscle does not pump ...


Other

Ultragenyx_GTX-102-CL301

GTX-102 is a human ubiquitin-protein ligase E3A antisense (UBE3A-AS) transcript-targeted antisense oligonucleotide (ASO) intended for the treatment of Angelman syndrome (AS). Findings from the Phase 1/2 dose-finding study (GTX-102-001) suggest a positive efficacy signal and ...


Other

LY3884961 in Patients With Peripheral Manifestations of Gaucher Disease

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called LY3884961 in people with Gaucher disease (GD). GD causes the collection of fats in some organs and bones, ...