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The Citadel Embolization Device Study

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the Stryker Citadel Embolization Device for treating people with a brain aneurysm. A brain aneurysm is a bulging, ...


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Adjunctive Recombinant Human Plasma Gelsolin With Standard of Care for Moderate-to-Severe ARDS

The purpose of this study is to evaluate an experimental medication called gelsolin (recombinant human plasma gelsolin) in people who have moderate to severe acute respiratory distress syndrome (ARDS) due to pneumonia or other infections. ...


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Rejection Surveillance With Cell-Free DNA Versus Endomyocardial Biopsy in Heart Transplant

The purpose of this study is to compare the effectiveness of 2 approaches for monitoring heart transplant rejection with either a blood test that looks at cell-free DNA (fragments of DNA from the transplanted heart) ...


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Cyclic Irrigation of Vancomycin Hydrochloride and Tobramycin Sulfate in Exchange Arthroplasty

The purpose of this study is to allow access to the experimental VT-X7 Treatment System for patients who have a periprosthetic joint infection (PJI) in their knee or hip after a previous joint replacement surgery ...


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Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX)

The purpose of this study is to evaluate a drug called pafolacianine that attaches to cancer cells and lights up when seen through a special camera system. The study focuses on patients who have gastrointestinal ...