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168 results found


Other Endocrine System, Pancreas

MK-6482 Monotherapy in Advanced Pheochromocytoma/Paraganglioma and Pancreatic Neuroendocrine Tumors

The purpose of this study is to evaluate the investigational use of a drug called belzutifan (MK-6482) in people with certain types of pheochromocytoma/ paraganglioma (PPGL) and pancreatic neuroendocrine tumors (pNET). The study will examine ...


Brain and Nervous System

Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

The purpose of the study is to determine whether an investigational drug called pembrolizumab combined with standard-of-care stereotactic radiation therapy and surgery is safe and effective in patients with recurrent glioblastoma. Researchers will evaluate whether ...


Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...


Cervix

HPV and Post-Treatment Surveillance

The purpose of this study is to examine the association between high-risk human papillomavirus (hr-HPV) with cancer recurrence among women who have completed treatment for invasive cervical cancer. Participants will be asked to complete a ...


Non-Hodgkin Lymphoma

Alliance, A051902, Phase II, OL, T-cell Lymphomas, CHO(E)P vs CC-486- CHO(E)P vs duvelisib-CHO(E)P

Primary objective: To compare the complete remission (CR) rates by FDG PET/CT using the Lugano 2014 criteria following completion of treatment with duvelisib-CHO(E)P vs CHO(E)P and with CC-486-CHO(E)P vs CHO(E)P in previously untreated peripheral ...