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142 results found


Pancreatic Cancer

Perioperative Versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer

The purpose of this study is to compare the usual treatment approach (surgery followed by chemotherapy) to using chemotherapy followed by surgery and then more chemotherapy in people with removable pancreatic cancer. The addition of ...


Melanoma

Early Discontinuation of Anti-PD-1 Therapy in Patients With Advanced Melanoma

This study focuses on individuals who have advanced melanoma cancer that is currently being treated with one immunotherapy drug (anti-PD-1 drugs nivolumab or pembrolizumab) or a combination of nivolumab and ipilimumab. Researchers aim to determine ...


Cancer of the mouth and throat associated with HPV

Chemoradiation Following Robotic Surgery for Oropharyngeal Cancer

This study focuses on individuals who have been diagnosed with HPV-associated oropharyngeal cancer and have had or will require surgery to remove their cancer prior to starting chemoradiation. The purpose of the study is to ...


Kidney

Immunotherapy-Based Combination Therapy With Or Without Cytoreductive Nephrectomy

This study focuses on individuals who have newly diagnosed kidney cancer that has spread outside of the kidney (metastatic kidney cancer) and who have not started therapy or just recently started their first therapy. Patients ...


Pancreas

Johns Hopkins University; EIIT2020-Osipov; Ph 2; OL; PDAC; Pembrolizumab with or without Defactinib

This study focuses on patients who have been recently diagnosed with high-risk pancreatic cancer and whose cancer was determined to be surgically removable (resectable). The purpose of the study is to evaluate the effectiveness (anti-tumor ...