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155 results found


Colon, Esophagus, Pancreas, Rectum, Small Intestine, Stomach

Ketamine for the Treatment of Anxiety in Patients With Pancreatic Cancer

Patients diagnosed with pancreatic cancer have a high rate of anxiety. In previous studies, low dosages of ketamine have been shown to rapidly decrease symptoms of anxiety (and depression), with few side effects, in a ...


Colon

Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer

The purpose of this study is to evaluate the effectiveness and safety of specially selected, multiple therapies in patients with metastatic colorectal cancer (mCRC). The study will evaluate the effects of an experimental drug called ...


Prostate

NRG, NRG-GU010, Ph 3, Open Label, Prostate, RT vs. RT + ADT vs. RT + ADT + Darolutamide

1.1 Primary Objectives: 1.1.1 De-Intensification Study: To determine whether men with National Comprehensive Cancer Network (NCCN) unfavorable intermediate risk (UIR) prostate cancer and lower Decipher genomic risk (Decipher score < 0.40) treated with RT alone instead of ...


Breast, Colon, Esophagus, Kidney, Lung, Melanoma, Ovary

Shionogi, 2023P2411(aCCeleR8-001), Ph1b/2,Open,Advanced Solid Tumors,S-531011 +/- Pembrolizumab

Primary: -To evaluate the safety and tolerability of S-531011 and to determine the MTD and/or RP2D of S-531011. Secondary: - To evaluate the preliminary antitumor activity of S-531011 per RECIST version 1.1a. - To characterize the PK profile ...


Breast cancer

Deescalation Of Breast Radiation for Treatment of Stage I Breast Cancer

This study focuses on women with low-risk breast cancer who have had lumpectomy (surgery to remove a breast lump). The purpose of the study is to compare the usual treatment of breast radiation and hormonal ...