Find Clinical Trials | Cedars-Sinai

38 results found

Ulcerative colitis

Vedolizumab Dual Targeted Therapy with Tofacitinib in Ulcerative Colitis

The purpose of this study is to determine whether combining medications for ulcerative colitis (vedolizumab with tofacitinib) is safe and improves symptoms of the disease. This treatment combination is referred to as “dual targeted therapy” ...

Other

Phase II Study of Unresectable Hepatocellular Carcinoma and Cirrhosis

The purpose of this study is to evaluate the effects of combined immunotherapy regimens (atezolizumab with bevacizumab) in patients with inoperable liver cancer and liver disease (cirrhosis). Participants may receive atezolizumab alone (if they are ...

Ulcerative colitis

MK-7240 in Moderately to Severely Active Ulcerative Colitis

The purpose of this research is to evaluate the safety and effectiveness of an experimental drug called MK-7240 (tulisokibart) compared with placebo (inactive substance) in people with moderately to severely active ulcerative colitis. There are ...

Other

Tulisokibart in Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) in people with moderately to severely active Crohn’s disease that has not responded well to treatment. ...

Ulcerative colitis

Etrasimod’s Effects on Vascular Pathobiology Using IUS: A Potential Marker of Early Response in Ulcerative Colitis

This study focuses on people with ulcerative colitis (an inflammatory disease of the bowel) who are starting a drug called etrasimod as standard of care. The study aims to show that etrasimod reduces abnormal blood ...