Find Clinical Trials | Cedars-Sinai

63 results found

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AZD3427 in Heart Failure and Pulmonary Hypertension Due to Left Heart Disease

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an experimental drug called AZD3427, given in addition to standard-of-care medication, in patients with heart failure and pulmonary hypertension due to ...

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SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...

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Volumetric Echocardiographic Imaging for MR

(1) To study the feasibility of V-Echo-PIV to quantify MR and thus eliminate intra- and inter-operator variability in grading MR. (2) To develop a robust methodology for noninvasive quantification and grading of mitral valve regurgitation (MR) by means ...

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Functional Characterization of Post-Heart Transplant De Novo Donor Specific Antibodies

The purpose of this study is to identify unique characteristics of pathological donor-specific antibodies (DSAs). Pathological DSAs cause injury to the transplanted heart (also known as graft injury), unlike DSAs that may have attained immunological ...

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Treprostinil Therapy to Reverse Right Ventricular Remodeling in Pulmonary Arterial Hypertension

The purpose of this study is to evaluate whether giving a drug called treprostinil earlier in a patient’s pulmonary arterial hypertension (PAH) diagnosis and then quickly increasing the dose will improve the patient’s PAH symptoms ...