Find Clinical Trials | Cedars-Sinai

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Aficamten Compared to Placebo in Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to compare the effects of an experimental drug called aficamten and placebo (inactive substance) on the exercise capacity and health status of patients with symptomatic, non-obstructive hypertrophic cardiomyopathy (nHCM). ...

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AstraZeneca_D8330C00003_REPHIRE

Primary - To evaluate the effect of AZD3427 on PVR after 24 weeks of treatment in participants with HF and PH Group 2 Secondary - To evaluate the effect of AZD3427 on additional hemodynamic markers of ...

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SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...

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Functional Characterization of Post-Heart Transplant De Novo Donor Specific Antibodies

The purpose of this study is to identify unique characteristics of pathological donor-specific antibodies (DSAs). Pathological DSAs cause injury to the transplanted heart (also known as graft injury), unlike DSAs that may have attained immunological ...

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Early Feasibility Study of the Trisol System Protocol

The purpose of this study is to evaluate the safety and effectiveness of the experimental Trisol System (TRISOL Valve System) in people who have tricuspid regurgitation (TR). TR is a condition in which the heart’s ...