Find Clinical Trials | Cedars-Sinai

73 results found

Other

Triscuspid Regurgitation: Edwards PASCAL TranScatheter Valve Repair System

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the PASCAL System with optimal medical therapy (OMT) compared to OMT alone in patients with symptomatic severe tricuspid ...

Pulmonary hypertension

Pulmonary Hypertension: Sotatercept versus Placebo (CADENCE)

This study focuses on individuals who have been diagnosed with a form of pulmonary hypertension (PH) associated with left heart disease, known as heart failure with preserved ejection fraction (HFpEF). PH is a disease affecting ...

Congenital heart, Familial hypercholesterolemia

Bempedoic Acid in Pediatric Patients With Heterozygous Familial Hypercholesterolemia

The purpose of this study is to evaluate the investigational use of a drug called bempedoic acid in individuals who have heterozygous familial hypercholesterolemia (HeFH). HeFH is a condition in which there are higher-than-normal amounts ...

Congenital heart

Medtronic Harmony TPV Post-Approval Study

The purpose of this study is to evaluate the functionality of transcatheter implantation (a minimally invasive procedure) of the Medtronic Harmony Transcatheter Pulmonary Valve (TPV). Significant pulmonary regurgitation (abnormal reversal of blood flow in the ...

Heart failure

Implantable CCM in the Heart Failure Group With Higher Ejection Fraction

The purpose of this study is to determine whether cardiac contractility modulation (CCM), a heart failure device therapy that improves contraction of the heart, will reduce cardiovascular mortality and heart failure hospitalizations in certain patients. ...