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25 results found


Amyotrophic lateral sclerosis (ALS), Neural Progenitor Cells, Stem Cells

CNS10-NPC-GDNF Delivered to the Motor Cortex for the Treatment of ALS

This study focuses on individuals who have been diagnosed with amyotrophic lateral sclerosis (ALS), with symptoms present for less than 3 years.  The purpose of the study is to examine the safety and effectiveness of ...


Parkinson's Disease

Parkinson's Disease: Non-Invasive Brainstem Modulation for the Management of Non-Motor Symptoms

This study focuses on individuals who have Parkinson's disease (PD) and are fully vaccinated from COVID-19 (coronavirus). The purpose of the study is to evaluate the safety and effectiveness of an investigational neuromodulation device for ...


Primary lateral sclerosis (PLS)

Primary Lateral Sclerosis Natural History Study

Primary lateral sclerosis (PLS) has been largely neglected in terms of research, primarily because it is so rare. The purpose of this study is to change the current research status of PLS by collecting clinical ...


Alzheimer's disease, Memory Disorders

AVP-786 for the Treatment of Agitation in Dementia of the Alzheimer's Type

This study focuses on individuals who have been diagnosed with probable Alzheimer’s disease (AD) and have agitation. Agitated behaviors such as irritability and restlessness, physical/verbal aggression, pacing and wandering are major problems in Alzheimer’s patients. ...


Parkinson's Disease

CereGate Therapy to Reduce Freezing of Gait in Parkinson's Disease

The purpose of this study is to determine whether using CereGate therapy with deep brain stimulation (DBS) reduces freezing of gait in individuals diagnosed with Parkinson’s Disease (PD) who have been implanted with a Boston ...