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Benfotiamine in Patients With Early Alzheimer’s Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called benfotiamine as a possible treatment for Alzheimer’s disease (AD). Benfotiamine is a lab-made version of vitamin B1 (thiamine). ...


Other

Intraoperative Assessment of Tissue With Time-Resolved Fluorescence Spectroscopy

The purpose of this study is to evaluate the use of a device in the detection of tumor tissue versus normal tissue at the time of surgery. The technique used by the device is called ...


Movement Disorders

Syn-Sleep Study

The purpose of the study is to evaluate the use of an experimental test called the Syn-One Test for identifying patients with idiopathic rapid eye movement sleep disorder (iRBD) that will progress to synucleinopathies (a ...


Movement Disorders

Zoledronic Acid for Prevention of Fractures in Parkinson’s Disease and Parkinsonism

The purpose of this study is to determine whether a medicine called zoledronic acid can reduce fractures in people with Parkinson's disease or parkinsonism. People with Parkinson's disease or parkinsonism have a high risk of ...


Movement Disorders

Safety and Efficacy of AMX0035 in Progressive Supranuclear Palsy

This study focuses on people who have been diagnosed with progressive supranuclear palsy (PSP) or have a probable diagnosis of PSP. PSP is a nervous system disease that affects nerve cells in the brain and ...