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4 results found


Geriatrics, Metabolism, Obesity

Single Nuclei RNA-Seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

The purpose of this study is to evaluate whether senescent cells (cells that age and permanently stop dividing but do not die) affect the body’s ability to metabolize (process) sugars. Researchers will examine various cells ...


Dementia, Geriatrics, Statin

Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults

The purpose of this study is to determine whether a drug called atorvastatin (a type of statin) can help older adults live well for a longer period of time by preventing dementia, disability, or heart ...


Alzheimer's disease, Dementia, Geriatrics

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of Alzheimer's Disease

The purpose of this study is to determine whether a medication called emtricitabine is safe and tolerable in people with mild to moderate Alzheimer’s disease (AD). Researchers also want to learn whether emtricitabine has the ...


Diabetes (Type2), Endocrinology, Geriatrics

Endoscopic Intestinal Re-Cellularization Therapy in Type II Diabetes (ReCET Study)

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the ReCET Intestinal Cellular Regeneration System for improving glycemic (blood sugar) control in individuals with type 2 diabetes ...