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7 results found


Heart failure, Coronary Artery Disease

WISE HFpEF

We are doing this study in new cohorts of women and men with small vessel disease (a condition in which the small arteries in the heart become narrowed) and HFpEF (a condition with inadequate heart ...


Genetic Disorders of the Cardiovascular System, Heart failure

Cytokinetics (CK-3773274)

This study focuses on adults who have obstructive hypertrophic cardiomyopathy (oHCM), abnormally thick heart muscle, and left ventricular outflow tract (LVOT) obstruction (a condition which interferes with the flow of blood in the heart). The ...


Heart Transplant, Heart failure

Heart Transplant, Heart Failure: Evaluating the Safety of Utilizing Donor Hearts from Donation after Circulatory Death (DCD) Donors compared to Donor Hearts from Donation after Brain Death (DBD) Donors (DCD IIT)

The purpose of this study is to evaluate the safety of using hearts from donors after circulatory death (DCD) compared to hearts from donors after brain death (DBD) in individuals who have been listed to ...


Heart failure

Heart Failure and Reduced Ejection Fraction: A Pilot Study to Increase Utilization of Guideline Directed Medical Therapy in Patients with Heart Failure and Reduced Ejection Fraction Using a Digital Therapeutics Platform

Primary -Percentage of time that the treating clinician agrees with the DE GDMT medication recommendations. For this endpoint, all patients will be considered regardless of enrollment time and will begin after RPM has been initiated. Key Secondary -The ...


Heart failure

Heart Failure: In-Hospital Initiation of Dapagliflozin in Acute Heart Failure (DAPA ACT HF-TIMI 68)

The purpose of this study is to evaluate whether a drug called dapagliflozin is safe and effective when added to conventional heart failure therapy in patients who have been admitted to the hospital for acute ...