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135 results found


Prostate

Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

This study will evaluate an experimental drug called carotuximab when taken in combination with apalutamide, in comparison to apalutamide alone, for the treatment of metastatic, castration-resistant prostate cancer. Carotuximab is a genetically engineered antibody (type ...


Breast cancer

T-DM1 and Placebo Compared With T-DM1 AND Tucatinib in HER2-Positive Breast Cancer

This study focuses on patients who have human epidermal growth factor receptor 2 (HER2)-positive breast cancer and who have already received treatment with chemotherapy and anti-HER2 targeted therapies followed by surgery. The study will evaluate ...


Lung

Open vs. Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

The purpose of this study is to compare the effects of 2 surgery methods for people with bone cancer (osteosarcoma- OST) that has spread to the lung. The 2 types of surgeries are called open ...


Breast cancer

Ivermectin and Balstilimab in Metastatic Triple Negative Breast Cancer

The purpose of this study is to evaluate whether concurrent use of oral ivermectin and intravenous (IV) balstilimab is safe and effective in treating patients with triple negative breast cancer. Researchers want to know the ...


Breast cancer, Colon cancer, Lung Cancer, Melanoma, Rectal Cancer, Solid ...

GV20-0251 in Advanced and/or Refractory Solid Tumor Malignancies

The purpose of the study is to determine whether an experimental drug called GV20-0251 is safe and tolerable in patients with solid tumors that have not been successfully treated with standard therapies. GV20-0251 is a ...