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155 results found


Lung

Bevacizumab in Combination With Chemoimmunotherapy and Maintenance Atezolizumab in Extensive Stage Small Cell Lung Cancer and Liver Metastases

This study focuses on individuals who have been diagnosed with extensive-stage, small cell lung cancer with liver metastases (cancer that has spread to the liver). The study will evaluate the addition of a drug called ...


Melanoma

IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in Advanced Melanoma

This study focuses on adults with advanced melanoma (a type of skin cancer) that has spread or cannot be surgically removed. The purpose of the study is to determine whether an experimental drug called IMC-F106C, ...


Prostate

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

The purpose of this study is to determine whether a commonly used cholesterol-lowering therapies can help recruit antitumor immune cells into a prostate tumor. The study focuses on people with prostate cancer who have elected ...


Unknown Sites

Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers

The purpose of this study is to evaluate how the combination of the drugs nivolumab and relatlimab might work in people with advanced cancer that is “microsatellite instability high” (MSI-H). Microsatellite instability is a marker ...


Myeloid and Monocytic Leukemia

MYELOMATCH, Master Screening and Reassessment Protocol

In this study, researchers will plan various treatment substudies for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have not yet started treatment. Participants will be asked to undergo testing on their ...