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162 results found


Lung Cancer, Non-small cell

IOV-4001 in Melanoma or Non-Small-Cell Lung Cancer

The purpose of this study is to determine whether an investigational drug called IOV-4001 is safe and beneficial in the treatment of patients with unresectable or metastatic melanoma or advanced non-small cell lung cancer (NSCLC). ...


Breast

Reinvigorating TNBC Response to Immunotherapy With Myeloid Inhibition and Radiation

The purpose of this study is to examine the feasibility, safety, and effectiveness of an experimental combination therapy of the drug axatilimab, radiation to the tumor, and pembrolizumab (another drug) in patients who have been ...


Prostate

Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

This study will evaluate an experimental drug called carotuximab when taken in combination with apalutamide, in comparison to apalutamide alone, for the treatment of metastatic, castration-resistant prostate cancer. Carotuximab is a genetically engineered antibody (type ...


Lung

Open vs. Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

The purpose of this study is to compare the effects of 2 surgery methods for people with bone cancer (osteosarcoma- OST) that has spread to the lung. The 2 types of surgeries are called open ...


Breast cancer

Ivermectin and Balstilimab in Metastatic Triple Negative Breast Cancer

The purpose of this study is to evaluate whether concurrent use of oral ivermectin and intravenous (IV) balstilimab is safe and effective in treating patients with triple negative breast cancer. Researchers want to know the ...